Dear DUPIXENT –
All I can say is thank you! I had been struggling with asthma for
over 30 years, and I had tried so many other treatments. So, when my doctor first introduced me to
DUPIXENT, I was very hesitant. Over time, with DUPIXENT, I started to
notice a change. My breathing started to improve, and I was using my rescue
inhaler less and less. Today, I do not think about when my next
attack will be, and that has allowed me to DU More of the things I love, like playing
with my grandchildren. DUPIXENT has helped me better
manage my asthma, and I am very thankful!
Sincerely, Marlena Important Safety Information Do not use if you are allergic to
dupilumab or to any of the ingredients in DUPIXENT®.
Before using DUPIXENT, tell your healthcare provider about all your
medical conditions, including if you: • have a parasitic (helminth) infection
• are scheduled to receive any vaccinations. You should not receive
a “live vaccine” right before and during treatment with DUPIXENT.
• are pregnant or plan to become pregnant. It is not known whether
DUPIXENT will harm your unborn baby.
o A pregnancy registry for women who take DUPIXENT during
pregnancy collects information about the health of you and your
baby. To enroll or get more information call
1-877-311-8972 or go to https://mothertobaby.org/ ongoing study/dupixent/.
• are breastfeeding or plan to breastfeed. It is not known whether
DUPIXENT passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription
and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or
inhaled corticosteroid medicines or use an asthma medicine. Do not change or
stop your corticosteroid medicine or other asthma medicine without talking to your
healthcare provider. This may cause other symptoms that were controlled by
the corticosteroid medicine or other asthma medicine to come back.
DUPIXENT can cause serious side effects, including:
• Allergic reactions. DUPIXENT can cause allergic reactions that
can sometimes be severe. Stop using DUPIXENT and tell your
healthcare provider or get emergency help right away if you
get any of the following signs or symptoms: breathing problems or
wheezing, swelling of the face, lips, mouth, tongue, or throat,
fainting, dizziness, feeling lightheaded, fast pulse, fever,
hives, joint pain, general ill feeling, itching, skin rash, swollen lymph
nodes, nausea or vomiting, or cramps in your stomach-area.
• Inflammation of your blood vessels. Rarely, this can happen
in people with asthma who receive DUPIXENT. This may happen in
people who also take a steroid medicine by mouth that is being
stopped or the dose is being lowered. It is not known whether
this is caused by DUPIXENT. Tell your healthcare provider right
away if you have: rash, chest pain, worsening shortness of breath, a
feeling of pins and needles or numbness of your arms or legs, or
persistent fever. • Joint aches and pain. Some people
who use DUPIXENT have had trouble walking or moving due to their joint
symptoms, and in some cases needed to be hospitalized. Tell your
healthcare provider about any new or worsening joint symptoms. Your
healthcare provider may stop DUPIXENT if you develop joint
symptoms. The most common side effects in
patients with asthma include injection site reactions, high count of a certain
white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic
(helminth) infections. Tell your healthcare provider if you have
any side effect that bothers you or that does not go away. These are not all the
possible side effects of DUPIXENT. Call your doctor for medical advice about side
effects. You are encouraged to report negative side effects of prescription drugs
to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection
given under the skin (subcutaneous injection). Your healthcare provider will
decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and
inject DUPIXENT until you or your caregiver have been trained by your
healthcare provider. In children 12 years of age and older, it’s recommended
DUPIXENT be administered by or under supervision of an adult. In children 6 to less than 12 years of age, DUPIXENT
should be given by a caregiver. Please see adjacent links for full
Prescribing Information including Patient Information.