>>> WE ARE BACK. IT'S 8:13. HOW EXCITED ARE YOU? >> I'M SO EXCITED. >> WE'RE EXCITED BECAUSE WE'RE SITTING HERE WITH THE LEGENDARY DEMI MOORE. >> THE LEGEND WILL GROW WITH THIS NEW MOVIE OF HERS. SHE STARS AS A FORMER A LISTER WHO WAS FIRED FROM HER TV SHOW FOR BEING TOO OLD. WELL, DOWN AND OUT, SHE COMES ACROSS AN OPPORTUNITY TO CHANGE HER LIFE WITH A MYSTERIOUS NEW DRUG. TAKE A LOOK. >> HAVE YOU EVER DREAMT OF A BETTER VERSION OF YOURSELF? YOUNGER, MORE BEAUTIFUL, MORE PERFECT. ONE SINGLE INJECTION UNLOCKS YOUR DNA, STARTING A NEW CELLULAR DIVISION THAT WILL RELEASE ANOTHER VERSION OF YOURSELF. THIS IS THE SUBSTANCE. >> THIS IS "THE SUBSTANCE". >> GOOD MORNING. IT IS SUCH A PLEASURE TO HAVE YOU HERE. >> THANK YOU FOR HAVING ME. >> I'M VERY, VERY EXCITED BECAUSE I'M A HUGE FANS OF YOURS. HOW DO WE DESCRIBE THIS MOVIE? IT IS RIVETING AND SHOCKING, WOULDN'T YOU SAY? >> I THINK ALL OF THE ABOVE. THE VERY SHORT VERSION BECAUSE IT IS SOMEWHAT DIFFICULT TO FULLY ENCAPSULATE. AS I SAID, IT IS A LITTLE BIT LIKE THE PICTURE DORIAN GRAY MEETS "DEATH BECOMES HER" WITH A JANE FONDA WORKOUT. THAT'S KIND OF THE LOOSE VERSION. BUT I THINK IT REALLY IS A VERY UNIQUE WAY OF REALLY DELVING INTO A RELEVANT SUBJECT MATTER, WHICH IS AGING, THE PERCEPTION, THE COLLECTIVE CONSCIOUSNESS OF WOMEN'S VALUE DIMINISHING AS WE GET OLDER, WHICH JUST ISN'T THE TRUTH. BUT IN THIS CASE, IT KIND OF IS REPRESENTING SOME OF THE OLD IDEALS. >> YES. I SHOULD JUST SAY IT IS VERY, VERY GORY AND BLOODY BY THE END. AND YOUR PERFORMANCE IS SO GUTSY AND BRAVE. WHAT DID YOU THINK WHEN THEY CAME TO YOU WITH THIS SCRIPT, WHAT'S REQUIRED OF YOU, WHAT THE SCRIPT -- WHAT IS UNFOLDING IN THIS MOVIE? YOU MUST HAVE BEEN TERRIFIED. >> IT WAS DEFINITELY SOMETHING THAT I KNEW WAS GOING TO REALLY PUSH ME OUT OF MY COMFORT ZONE. BUT IT HAD A LOT OF CHALLENGES, NOT JUST PHYSICALLY, WHICH THERE IS A LOT OF THAT, BUT EMOTIONALLY, THE LEVEL OF KIND OF RAW VULNERABILITY THAT IT WAS GOING TO REQUIRE. BUT THE MESSAGE FOR ME THAT WAS SO POWERFUL IN THIS IS NOT WHAT'S HAPPENING IN THE CIRCUMSTANCES AROUND, BUT IT'S THE VIOLENCE THAT WE HAVE AGAINST OURSELVES. AND THAT'S WHAT I FEEL WAS REALLY POWERFUL IN THIS. >> WELL, IT SEEMS LIKE IT'S RESONATING WITH A LOT OF PEOPLE. YOU HAVE A 13-MINUTE STANDING OVATION AT CAAN. YOU'RE GETTING ALL KINDS OF RAVE REVIEWS. ONE OF THE MAGAZINES WROTE, THE PERFORMANCE OF YOUR CAREER. IT IS GETTING OSCAR BUZZ. I MEAN, ALL OF THIS AT THIS POINT IN YOUR LIFE. YOU'RE 61. I JUST TURNED 60. I FEEL LIKE ALL KINDS OF NEW THINGS ARE HAPPENING. >> YES. >> WHERE ARE YOU AT THIS POINT LIKE IN YOUR LIFE AND CAREER? >> I MEAN, I FEEL LIKE IT'S -- FIRST OF ALL, I REALLY TRY TO BE AS PRESENT IN THE MOMENT AS POSSIBLE. >> YEAH. >> AND WHAT I FEEL FROM THAT IS AN EXCITEMENT OF POSSIBILITY THAT ARE REALLY -- THAT WE'RE DEFINING A NEW -- A NEW -- I DON'T WANT TO SAY A GENERATION, BUT WE ARE WHAT THE FUTURE IS FOR WOMEN. >> YEAH. >> AND I LOOK AT HAVING MY DAUGHTERS, AND I DON'T WANT THERE TO EVER BE IN THEIR MINDS THAT THERE IS AN END. TO ME, THIS IS THE MOST EXCITING TIME OF MY LIFE. >> THE MOST EXCITING TIME OF YOUR LIFE? >> YES. >> THAT SOUNDS SO GOOD RIGHT NOW. >> IT IS. I FEEL LIKE MY CHILDREN ARE GROWN. I HAVE THE MOST INDEPENDENCE AND AUTONOMY TO REALLY RE-DEFINE WHERE I WANT TO GO. I DON'T KNOW WHAT THAT LOOKS LIKE OR WHERE IT IS, BUT I'M JUST EXCITED TO BE LIVING IN IT. >> AND IT REALLY -- IT KIND OF GOES ALONG WITH THE MOVIE BECAUSE THE MOVIE IS SO MUCH ABOUT, AS YOU SAID, THE VIOLENCE WE DO TO OURSELVES, THE HATRED WE COULD HAVE FOR OUR BODIES, THESE UNREALISTIC EXPECTATIONS THAT ARE PLACED UPON US. AND YOU LIVED IT. IT IS WONDERFUL TO SAY, AND I CAME OUT THE OTHER SIDE. >> PART OF THE DYNAMIC IS I'M NOT ELIZABETH. THIS IS A WOMAN WHO HAS ONLY HER CAREER, ONLY -- ONLY THAT WHICH SHE'S PAVED THROUGH HER WORK. SHE HAS NO FAMILY. AND SO OFTEN, WE PLACE TOO MUCH IMPORTANCE ON THE EXTERNAL MARKERS. AND I THINK WHAT THIS IS REALLY ALSO TRYING TO SAY IS, YOU KNOW, WHERE IS OUR REAL PRIORITY? WHERE IS OUR REAL LOVE? WHERE DOES OUR REAL JOY COME FROM? IT CAN ONLY COME THROUGH THAT SELF-LOVE, SELF-ACCEPTANCE. >> WHAT'S INTERESTING WHEN IT COMES TO WHAT WE THINK ABOUT OUR BODIES, I WAS READING ABOUT YOU AND I THOUGHT, DEMI PROBABLY ALWAYS LOVED HER BODY BECAUSE EVERYONE WANTED DEMI'S BODY. YOU SAY NO. YOU WEREN'T IN LOVE WITH HOW YOU WERE LOOKING. YOU FELT LIKE A LOT OF US. >> NO, NO. AND I ALSO PUT A LOT OF -- I PLACED A LOT OF VALUE ON WHAT MY BODY LOOKED LIKE AS BEING A DEFINING MARKER OF WHETHER I BELONGED OR NOT, WHETHER I COULD SUCCEED OR NOT, ALL OF THOSE THINGS, WHICH, AGAIN, IS A BIG PART OF THE THEME IN THE FILM, WHICH IT'S REALLY LOOKING AT. I THINK SOMETIMES PEOPLE HAVE LOOKED AT THIS AS REALLY EXPLORING THE IDEA OF WHAT THE PRESSURES OF THE EXTERNALS, LIKE WHAT IS SOCIETY -- WHICH DO EXIST. BUT AT THE END OF THE DAY, IT IS THE VIOLENCE OF HOW WE LOOK IN THE MIRROR, THE COMPARE AND DESPAIR THAT LEAVES US FEELING SO BANKRUPT. >> WELL, THE IRONY IS, OF COURSE, BECAUSE YOU ARE A DROP DEAD GORGEOUS WOMAN HERE AND IN THIS MOVIE AND YET COULD STILL GRAPPLE WITH THESE FEELINGS. I THINK PEOPLE WILL CONNECT WITH THAT VERY MUCH. LET'S ASK YOU ABOUT YOUR FAMILY. THE KIDS ARE GROWN UP NOW. YOU ARE A GRANDMA NOW. YOU ARE AN AWESOME GRANDMA. >> I LOVE IT. I AM YAYA. AND SHE IS THE CUTEST. RUMOR SENT ME A PHOTO WITH SPA GETTY ON HER HEAD. >> WE HAVE TO ASK YOU ABOUT "SAINT ELMO'S FIRE." >> WE ARE ALL IN CONVERSATION. I THINK THE STUDIO HAS REALLY BEEN DRIVING THIS. AS FAR AS I KNOW, EVERYONE IS KIND OF IN AND GUNG HO. IT WOULD REALLY -- THAT WOULD BE SO FUN. >> YEAH. >> PLEASE DO THAT. >> CAN YOU? >> WE NEED TO DO THAT. >> THANK YOU SO MUCH. >> MY PLEASURE. >> DEMI, THANK YOU SO MUCH. CONGRATS ON THE MOVIE. IT IS CALLED "THE SUBSTANCE." PUBLIC SERVICE